Vitamin B-6 (pyridoxine) is important for normal brain development and for keeping the nervous system and immune system healthy.

Symptoms of B6 deficiency are:

• Skin Rashes.
• Cracked and Sore Lips.
• Sore, Glossy Tongue.
• Mood Changes.
• Weakened Immune Function.
• Tiredness and Low Energy.
• Tingling and Pain in Hands and Feet.
• Seizures

People who have kidney disease or conditions that prevent the small intestine from absorbing nutrients from foods (malabsorption syndromes) are more likely to be vitamin B-6 deficient. Certain autoimmune disorders, some epilepsy medications and alcohol dependence also can lead to vitamin B-6 deficiency. This can cause a condition in which you don't have enough healthy red blood cells to carry adequate oxygen to your body's tissues (anemia), confusion, depression and a weakened immune system.

A vitamin B-6 deficiency is usually coupled with deficiency in other B vitamins, such as folic acid (vitamin B-9) and vitamin B-12